Spartak Moskva 2 x 1 NapoliAleksandr Sobolev 3' (pênalti), Aleksandr Sobolev 28', Eljif Elmas 64'
FC Midtjylland 3 x 2 Sporting BragaErik Sviatchenko 2', Ricardo Horta 43', Gustav Isaksen 48', Galeno 85', Evander 90' (pênalti)
Crvena Zvezda 1 x 0 LudogoretsMirko Ivanic 57'
Galatasaray 4 x 2 Olympique MarseilleAlexandru Cicâldău 12', Duje Caleta-Car 30' (gol contra), Sofiane Feghouli 64', Arkadiusz Milik 68', Ryan Babel 83', Arkadiusz Milik 85'
Lokomotiv Moskva 0 x 3 LazioCiro Immobile 56' (pênalti), Ciro Immobile 63' (pênalti), Pedro 87'
Bayer 04 Leverkusen 3 x 2 CelticRobert Andrich 16', Josip Juranovic 40' (pênalti), Jota 56', Robert Andrich 82', Moussa Diaby 87'
Real Betis 2 x 0 FerencvárosiCristian Tello 5', Sergio Canales 52'
Dinamo Zagreb 1 x 1 GenkLuka Menalo 35', Iké Ugbo 45'
SK Rapid 0 x 2 West Ham UnitedAndriy Yarmolenko 39', Mark Noble 45' (pênalti)
Rangers 2 x 0 Sparta PrahaAlfredo Morelos 15', Alfredo Morelos 49'
Brøndby IF 1 x 3 Olympique LyonnaisMikael Uhre 50', Rayan Cherki 57', Rayan Cherki 66', Islam Slimani 76'
PSV 2 x 0 Sturm GrazCarlos Vinícius 45' (pênalti), Bruma 55'
Mônaco 2 x 1 Real SociedadKevin Volland 28', Alexander Isak 35', Youssouf Fofana 37'
Leicester City 3 x 1 Legia WarszawaPatson Daka 11', James Maddison 21', Filip Mladenovic 26', Wilfred Ndidi 33'
Olympiacos F.C. 1 x 0 FenerbahçeTiquinho Soares 89'
Eintracht Frankfurt 2 x 2 AntwerpDaichi Kamada 13', Radja Nainggolan 33', Ally Samatta 88', Gonçalo Paciência 90'
FC Midtjylland3 x 2
Sporting Braga14:45
Crvena Zvezda1 x 0
Ludogorets14:45
Galatasaray4 x 2
Olympique Marseille14:45
Lokomotiv Moskva0 x 3
Lazio14:45
Bayer 04 Leverkusen3 x 2
Celtic14:45
Real Betis2 x 0
Ferencvárosi14:45
Dinamo Zagreb1 x 1
Genk14:45
SK Rapid0 x 2
West Ham United17:00
Rangers2 x 0
Sparta Praha17:00
Brøndby IF1 x 3
Olympique Lyonnais17:00
PSV2 x 0
Sturm Graz17:00
Mônaco2 x 1
Real Sociedad17:00
Leicester City3 x 1
Legia Warszawa17:00
Olympiacos F.C.1 x 0
Fenerbahçe17:00
Eintracht Frankfurt2 x 2
Antwerp